Rheumatoid arthritis is a major ailment among rheumatic disorders. A large number of herbal extracts are in vogue used for treatment of various types of rheumatic disorders. Acacia catechu willd, an Indian herb was reported to have anti-inflammatory as well as analgesic activity, in-vitro as well as in-vivo. The present study deals with anti-arthritic activity in-vitro. Various in-vitro anti-arthritic pharmacological models were studied, such as, inhibition of protein denaturation, effect of membrane stabilization, and proteinase inhibitory action Herbal extract. All the in-vitro models i.e. inhibition of protein denaturation, membrane stabilization and proteinase inhibition were carried out with standard reference drug diclofenac sodium.
Acacia catechu willd, Anti-arthritic, Proteinase inhibitory, protein denaturation, Membrane Stabilization
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